Our Testing Services
PHARMACOGENOMICS(PGx)
PHARMACOGENOMICS (PGx), is one of the most exciting fields of personalized medicine today. It is an example of the field of precision medicine in which medical treatment of each person is tailored according to their condition. Pharmacogenomics studies each person’s DNA and how it responds to different drugs. Different patients respond to treatments differently so pharmacogenomics helps predict who will benefit from medication and who will have adverse reactions to it based on their DNA. Researchers have found out genetic variations in how people respond to different treatments and this information can be used to select the appropriate treatment for each person. New approaches to this infant field are being introduced and tested in clinical trials. Tailored treatment of many health problems such as cardiovascular disease, cancer, and HIV/AIDS has been introduced.
GENETIC PANEL
Devansh Lab Werks tests for genetic variants that can aid better prescription practices for more than 100 drugs in the following therapeutic areas:
- Psychiatric
- Pain & Addiction
- Oncology
- Cardiac
Tests Under PGx
Comprehensive Panel (30 Genes)
- ABCG2
- ADRA2A
- ANKK1
- ApoE
- BDNF
- CACNA1C
- COMT
- CYPNA2
- CYP2B6
- CYP2CY19
- CYP2C9
- CYP4F2
- CYP2D6
- CYP3A4
- CYP3A5
- DBH
- F2
- F5
- MTHFR
- GRIK4
- HTR2A
- HTR2C
- OPRK1
- OPRM1
- SLCO1B1
- TPMT
- VKORC1
- UGT2B15
- ABCB1
- SLC6A3/DAT1
Psychiatric Panel (14 Genes)
- ANKK1
- ApoE
- BDNF
- CACNA1C
- COMT
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- GRIKA
- HTR2A
- HTR2C
- OPRK1
Cardiac Panel (11 Genes)
- ApoE
- CYP2C19
- CYP2C9
- VKORC1
- CYP4F2
- CYP2D6
- CYP3A4
- F2
- F5
- MTHFR
- SLCO1B1
Oncology Panel (5 Genes)
- ABCG2
- ADRA2A
- CYP3A4
- CYP3A5
- TPMT
Pain And Addiction Panel (8 Genes)
- CYP1A2
- CYP2B6
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- CYP3A5
- OPRM1
FAQ's
Pharmacogenomics is the integration of pharmacology and genomics, analyzing how genetic variations influence drug responses. This field helps in precision medicine, allowing for customized medications that maximize effectiveness while minimizing adverse effects.
Genetic variations can impact drug metabolism, efficacy, and side effects. PGx testing identifies these differences, helping healthcare professionals recommend medications and dosages best suited for each individual. This approach enhances clinical decision-making and improves patient outcomes.
Pharmacogenomic testing is beneficial for individuals who:
→ Are about to start new medications
→ Experience adverse drug reactions (ADRs) or ineffective treatments
→ Take multiple medications (polypharmacy)
→ Have conditions like psychiatric disorders, cardiovascular diseases, or cancer
DLW provides a range of pharmacogenomic panels, including:
→ Comprehensive Panel (30 Genes): Covers genetic markers impacting 100+ drugs across psychiatric, pain, addiction, oncology, and cardiovascular treatments.
→ Psychiatric Panel (14 Genes): Targets genetic influences on psychiatric medication responses.
→ Cardiac Panel (11 Genes): Focuses on genes affecting cardiovascular drug metabolism.
→ Oncology Panel (5 Genes): Assesses genetic markers influencing cancer treatment drugs.
→ Pain and Addiction Panel (8 Genes): Evaluates genetic factors in pain management and addiction therapies.
A healthcare professional collects a buccal swab (cheek swab) or blood sample. The DNA is analyzed in a CLIA-certified laboratory to identify genetic markers influencing drug response, ensuring accurate diagnostic testing.
By identifying genetic factors affecting drug metabolism, pharmacogenomic testing enables:
→ Selection of medications with higher efficacy.
→ Dosage adjustments for optimized therapeutic levels
→ Avoidance of high-risk drugs to prevent severe side effects
→ Reduction in trial-and-error prescriptions, improving personalized medicine
Coverage varies based on insurance providers and policies. Many healthcare insurers cover PGx testing if it is deemed medically necessary. It is recommended to verify coverage with your insurance provider.
DLW utilizes advanced molecular diagnostics to provide highly accurate pharmacogenomic test results in the shortest possible time. The quick turnaround ensures timely clinical decisions for personalized treatment plans.
Pharmacogenomics enhances patient-centered care by examining genetic factors that impact drug reactions. This enables:
→ Identification of optimal medications
→ Reduction in adverse drug reactions
→ Improved adherence to personalized treatment regimens
→ Greater efficiency in prescription accuracy
DLW’s pharmacogenomic testing services analyze a patient’s genetic profile to determine how their body processes medications. By pinpointing specific genetic markers, DLW helps healthcare providers prescribe safe, effective, and individualized treatments, improving patient well-being through precision-based prescribing.